YOU'RE THE JUDGE

2021.10.28 01:41 JosephStalin1953 YOU'RE THE JUDGE

OH NO
SET ME FREEEEEEEEEEEEEEEEEEEEEEE
submitted by JosephStalin1953 to teenagersbutpog [link] [comments]


2021.10.28 01:41 Thruvan21_ Im Single😅😅🤣🤣

Im Single😅😅🤣🤣 submitted by Thruvan21_ to tamilmemes [link] [comments]


2021.10.28 01:41 310austin 50 Million Hoge donated to the Top 5 Exchange wallet…now what?

Brand new hogler and I’m curious of the next steps since the 50M Hoge have been donated to the Top 5 Exchange Wallet.
For example: let’s say it’s decided that Hoge is to be added to Coinbase…what does that process look like? How long does it take? Etc.
submitted by 310austin to hoge [link] [comments]


2021.10.28 01:41 Aggravating-Bowl-505 What should i do when i found a maggot on tomatoes after buying?

So i wasnt looking and decided to buy one. When i get home to cut it, its slimy and have maggots on it. What should i do? I threw it away
submitted by Aggravating-Bowl-505 to NoStupidQuestions [link] [comments]


2021.10.28 01:41 Commodore64__ Digging Deeper into ENLV's Phase 1B, Current Phase 2B, and Beyond

Digging Deeper into ENLV's Phase 1B, Current Phase 2B, and Beyond Digging Deeper in the SOFA Score In my last DD, I introduced the reader to the SOFA Score. The Sofa Score is an objective score to determine the extent of a person's organ function or rate of failure. The score is based on six different scores, one each for the respiratory, cardiovascular, hepatic, coagulation, renal and neurological systems. Each score is calculate upon admission to the ICU and on a repeating 24 hour basis. It allows medical professionals to determine the overall organ failure status and rate of failure over time.
As shown in chart 1 and in the Table below, as the SOFA score increases the probability of death also increases.
Chart 1
SOFA SCORE RANGE MORTALITY RATE PER SCORE
0-6 Roughly 10% or Less
7-9 15-20%
10-12 40-50%
13-14 50-60%
15 Greater than 80%
15-24 Greater than 90%
ENLV's Phase 1B Results
ENLV treated 10 patients with an average age of 71.5 and 80%/20% male/female split. The treatment group had an average initial SOFA score of 3.4 and a SOFA range of 2-6 when they first were diagnosed in the ICU. In the retroactive comparative nontreatment cohort of 37, they were an average age of 71.5 and consisted of 80% male and 20% female. Their average SOFA score was 3.47 with a SOFA range of 2-7 when they were first diagnosed in the ICU. Over the course of 28 days the treatment group and the non-treatment group had drastically divergent changes in their SOFA scores. As you can see in chart 2 below, the treatment group's max change in SOFA score barely budged, suggesting that Allocetra (ENLV's innovative immunotherapy) may be a highly effective treatment at stopping the devastating progression of sepsis. Accordingly, these patients never progressed to higher SOFA scores with their associated higher risk of mortality. In the control group (non-treatment) we can observe significant changes of their initial SOFA score that placed many patients into higher SOFA scores that significantly increased their probability of dying.
Chart 2
In Table 2 below we see that over a 28 day period the change (delta) from baseline SOFA to Day 28 SOFA differed greatly between the treatment group and the control (non-treatment) group. The treatment group saw a max delta from baseline SOFA of 0.1, whereas the non-treatment group saw a max delta ranging from 0.6 to 5. Incredibly, zero patients in the treatment group died by day 28, whereas 10 of controls (non-treated) died.
Table 2
In chart 3 we see another drastic divergence between the treated group and the control group, which again suggests that Allocetra is a highly effective treatment.
Chart 3
Allocetra ensured that 100% of treated patients were alive with fully recovered organs by day 28. In the control group, only 41% were alive with fully recovered organs by day 28. Placebo effect likely cannot account for all of this.
PHASE 2B: Targeting Severe Sepsis In Phase 2B ENLV will treat 120-160 patients hospitalized with an initial SOFA score up to 10. Right off the bat, these patients are at an elevated risk for death compared to the patients treated in Phase 1B who had a lower average SOFA score. The primary end points are to evaluate safety and change in SOFA with a secondary end point of reducing mortality. Unlike the phase 1B clinical trial, this clinical trial will include placebo so there can be no doubt as to the effectiveness of Allocetra.

Table 3
WHAT TO EXPECT AFTER A SUCCESSFUL PHASE 2b If ENLV even repeats some of their amazing Phase 1b results in their Phase 2b trial we can expect Allocetra will be approved in European markets by end of 2022/beginning of 2023. ENLV will pivot immediately to conducting a phase 3 trial in a bid to gain FDA approval. For phase 3, we can expect the company will conduct test sites in Israel, Europe, and the United States.
In August 2021 ENLV reported they were in the process of designing and building a new cGMP (guided and enforced by FDA policies) Allocetra manufacturing plant in Israel. The initial facility will be 17,000 square feet with the capacity to expand up to 21,500 square feet in the future. This facility will support additional manufacturing capacity for ongoing clinical trials, future clinical trials and initial commercial production of Allocetra should regulatory approvals be granted in Europe and/or the USA. These are extremely positive signs that make me believe the company is preparing itself as a bright acquisition target, but I cannot discount the possibility they may even successfully go it on their own. Either route is a win for shareholders.
FINANCIALS & FUTURE SHARE PRICE & RISKS With ENLV's history of acquiring non-dilutive grants to fund research in conjunction with its zero debt, 91M cash on hand, a 16M annual burn rate, and only 18M authorized shares ENLV has a very bright future. Management will likely dilute shares around 4M shares after phase 2B results are announced, but at that point you shouldn't care. Why? Because it is very likely ENLV will release results that have never been seen before and we can likely expect a SAVA-like increase surrounding the company's share price. It would not surprise me if we see the share price grow and sustain themselves to the $50-$100 range shortly after Phase 2b results are announced. Assuming 22M authorized shares, and a share price of $75 the market cap of the company would be a mere 1.65B. Now remember the TAM for severe sepsis they are targeting in phase 2B is a 33B market. I think ENLV could easily command a share price of $100 after phase 2B is a success and achieve a market cap of merely 2.2B. Who am I joking.....ENLV is going to be $200-$300 after a successful Phase 2B and the market cap would only be 4.4B-6.6B. After Phase 3, it could be worth a staggering amount per share because they would poised to command the 33B TAM for severe sepsis like no one has ever before.
Is ENLV without risk? No. It's possible that it may not see success in treating severe sepsis. Much like Merck's Molnupiravir that only saw success in preventing the progression of Covid-19 in people BEFORE they were hospitalized (think Severe Covid-19) it is possible that ENLV may discover that Allocetra is unable to reverse sepsis after a certain point of progression (higher SOFA score) has been achieved. But as you stand on the door of the known and the unknown you can make a calculated estimate as you do your own DD. I believe ENLV has a strong chance of exploding in share price in the near future. I believe the market makers know this too and that is the primary reason they are currently unwilling to assume massive risk in selling calls out to 2023 or beyond. That may change in the coming months as there may be a scramble to acquire shares before interim data for Sepsis is released in early Q1 2022. If you like a binary play (think success or failure) with a asymmetrical risk and reward profile, ENLV is something you will want to learn more about. I believe the worst case scenario is that ENLV drops to about $5 per share if they fail phase2b.....90M cash on hand divided by 18M shares. But the best case scenario could be hundreds of dollars per share and beyond. As for me and my 6,000 shares all I can say is YOLO and I like the stock!
Disclaimer: This post is not medical or investment advice. It is provided for entertainment purposes only. Please consult with a qualified financial planneadvisor for investment advice. Avoid yellow snow and don't place cats and dogs in the same room. I have 6,000 shares and 5/2022 calls.
submitted by Commodore64__ to ENLV [link] [comments]


2021.10.28 01:41 TheBazzinator97 Can someone come take from my candy bowl!

Been sitting here for 2 and a half hours and no-one has come. I also have my Public map icon set to public so I don’t know what’s happening. PSN is TheGeeker69
submitted by TheBazzinator97 to Market76 [link] [comments]


2021.10.28 01:41 CKSavageJr Elephant Battery, 1864 Watercolour by William Simpson depicting the Indian Mutiny of 1857-58 [1875×1355]

Elephant Battery, 1864 Watercolour by William Simpson depicting the Indian Mutiny of 1857-58 [1875×1355] submitted by CKSavageJr to BattlePaintings [link] [comments]


2021.10.28 01:41 Southern_Region_3967 How do you manage loneliness when traveling and in a hotel m-th?

submitted by Southern_Region_3967 to consulting [link] [comments]


2021.10.28 01:41 Titanick6 Blood starved Revenant mural

Blood starved Revenant mural submitted by Titanick6 to apexlegends [link] [comments]


2021.10.28 01:41 BoeBames We know grampa we heard you the first 5 million times

We know grampa we heard you the first 5 million times submitted by BoeBames to PoliticalHumor [link] [comments]


2021.10.28 01:41 RealRussellDelgado I made this video on moving files very simply from one drive to another. I'm not entirely sure if this subreddit is for this stuff though. Just a dude wanting to help out.

I made this video on moving files very simply from one drive to another. I'm not entirely sure if this subreddit is for this stuff though. Just a dude wanting to help out. submitted by RealRussellDelgado to pcmasterrace [link] [comments]


2021.10.28 01:41 surroundedmoon Worth upgrading to SN850 from Samsung 970Pro

Currently have a Samsung 1tb 970 Pro, and was wondering if it worth it to upgrade to something like a WD_BLACK 2TB SN850 seeing that Windows 11 is not getting direct storage.
Do you think direct storage (when it is released) will make that much of a difference in gaming loading between the two drives?
submitted by surroundedmoon to buildapc [link] [comments]


2021.10.28 01:41 Fancypantsnic A true ride or die

A true ride or die submitted by Fancypantsnic to aww [link] [comments]


2021.10.28 01:41 badnewsmero Terri Runnels is my all time favorite 🥵

Terri Runnels is my all time favorite 🥵 submitted by badnewsmero to classicwwedivas [link] [comments]


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submitted by BinaryOptionAlliance to CryptoMarsShots [link] [comments]


2021.10.28 01:41 Sharp_Yoghurt_2924 I- not exactly the black i was expecting lol

I- not exactly the black i was expecting lol submitted by Sharp_Yoghurt_2924 to rivalstars [link] [comments]


2021.10.28 01:41 Sharp_Yoghurt_2924 I- not exactly the black i was expecting lol

I- not exactly the black i was expecting lol submitted by Sharp_Yoghurt_2924 to rivalstars [link] [comments]


2021.10.28 01:41 hopelesssol [DISC] At That Time, The Battle Began - Chapter 14

[DISC] At That Time, The Battle Began - Chapter 14 submitted by hopelesssol to MyReadingManga [link] [comments]


2021.10.28 01:41 ThaProtege A "Build-A-Mate" service was created. Which 5 qualities would you put in the machine to produce the "perfect mate" for you?

submitted by ThaProtege to AskReddit [link] [comments]


2021.10.28 01:41 supergoldfishyeet The band when the football team is down 4-52

The band when the football team is down 4-52 submitted by supergoldfishyeet to marchingband [link] [comments]


2021.10.28 01:41 timetravelingslowly XBox One controller stuck as mouse

This issue seems like it it's close to fixed, but so far I haven't had any luck with making effective change.
I'm running parsec through crouton on my Acer C315 and I've had great success with stability from the android app version. My issue comes with my controller (STANDARD GAMEPAD Vendor: 045e Product: 02fd) It is listed as an input device and the left joystick gets automatically mapped to the mouse. Xinput even happens to find all the analog inputs. BUT Xboxdrv doesn't seem to support the new controllers and doesn't recognize any devices.
The upshot is that I have a janky mouse, but nothing is able to actually use my controller. Gamepad tester, parsec, etc. Is there a package I'm missing? Has anyone else had this issue?
submitted by timetravelingslowly to Crouton [link] [comments]


2021.10.28 01:41 EricSchC1fr Fight breaks out after Catholic priest orders maskless man to leave church | Priest says man ‘has engaged in a course of abusive and threatening conduct, directed not just at me but towards the parish and school staff’.

Fight breaks out after Catholic priest orders maskless man to leave church | Priest says man ‘has engaged in a course of abusive and threatening conduct, directed not just at me but towards the parish and school staff’. submitted by EricSchC1fr to AnythingGoesNews [link] [comments]


2021.10.28 01:41 cumbetweenmytoesmmmm joe biden has passed away at the age of 189 😪

very sad news
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2021.10.28 01:41 Spiritual-Bowler-726 GEB is a horror movie

Watching Lonny Butcher dress up as three different girls in three different wigs in GEB 3006 is the scariest horror movie I've seen this fall.
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2021.10.28 01:41 Great-Juggernaut6541 A absolute original

A absolute original submitted by Great-Juggernaut6541 to Caveira_is_best_girl [link] [comments]


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